Syphilis

A Selection of Internet Sites

[*] Outstanding
[P] For Professionals
[S] Support Groups
[T] Teaching


Congenital Syphilis: still a reality in 1996
Michael D Humphrey et al.
The medical Journal of Australia. Syphilis continues to be a problematic health issue in many parts of the world. In Australia, congenital syphilis is again a significant cause of stillbirth, preterm labour and neonatal disease in some areas ... There is a need to raise awareness that antenatal care is important not only for the mother's health but also for the wellbeing of the baby.

[*][P] Teaching Files: Syphilis
Division of Neonatology, Cedars-Sinai Medical Center, Los Angeles, California. It remains unclear what factors determine which mothers, particulary those in latent stage of the infection, will pass the disease to their fetuses ... T. pallidum does not survive well outside the host, the only precaution that must be taken by health personnel caring for syphilis infants is to avoid touching the infectious lesions. Except for the open skin lesions and mucous membrane lesions of the neonate, congenital syphilis is not infectious by contact. Therefore, no special isolation procedure is required. Congenital syphilis is contracted from an infected mother via transplacental transmission of T. pallidum at any time during pregnancy or at birth. In women with untreated early syphilis, 40% of pregnancies result in spontaneous abortion, stillbirths, or perinatal deaths. Untreated syphilis, at any stage of disease, can be transmitted to the fetus; the rate of transmission is about 100% during the second stage. A stillborn syphilitic fetus has a macerated appearance with a collapsed skull and protuberant abdomen. The skin shows vesicular and bullous lesions which have a fluid rich in treponemes ...

[*][P] Syphilis, Congenital (Revised September 1996).
CDC. Case definitions for Infectious Conditions Under Public Health Surveillance. A wide spectrum of severity exists, and only severe cases are clinically apparent at birth. An infant or cild (aged less than 2 years) may have signs such as hepatosplenomegaly, rash, condyloma lata, snuffles ... An older child may have stigmata (e.g., interstitial Keratitis, nerve deafness, anterior bowing of shins ...

Syphilis, from: CDC. Case definitions for Infectious Conditions Under Public Health Surveillance
(All Definitions revised September 1996).
Syphilis, Primary ... Stillbirth ...

[*][P] Syphilis
National Institute of Allergy and Infectious Diseases Fact Sheet.

[*][P] Congenital Syphilis, (JAMA women┤s health)
1998 Guidelines for treatment of Sexually Transmitted Diseases. Effective prevention and detection of congenital syphilis depends on the routine serologic screening of pregnant women at the time of the first prenatal visit ...

[Spanish] Infecciones y Enfermedades
Infecciones de Aparato Reproductivo. Enfermedades de Transmisiˇn Sexual. Hechos bßsicos sobre la infecciˇn por VIH/SIDA ...

[French] La Syphilis
Index du Site. Contraception. Grossesse ...

[*] Antenatal Screening for Syphilis
Editorials, BMJ 1998;317:1605-1606. Much congenital infection is now preventable. Antenatal screening is an important measure in reducing vertical transmission of syphilis, hepatitis B, and HIV ...

[*] Links
Resources. Hellenic Association Dermatology-Venereology

[P] Prevention of Congenital Syphilis (Obstetric Focus)
Screening. Diagnosis and Treatment. Antibiotic Choice ...

[P] Infectious Disease Testing for Blood Transfusions
National Institute of Health Consensus Development Conference Statment. January 9-12, 1995
Conclusions ... The serum alanine aminotransferase test should be discontinued as a surrogate marker for blood donors likely to transmit posttransfusion non-A, non-B hepatitis antibody ... Syphilis testing should continue until adequate data can determine its effect on the rarity of transfusion-transmitted syphilis ...

Syphilis
What is syphilis? How does someone get syphilis? What is the impact of syphilis on pregnancy? How is syphilis diagnosed? ...

Syphilis
The National Women`s Health Information Center. How is syphilis spread and how can I avoid it? ...

Syphilis
National Sexually Transmitted Disease (STD) Hotline. Limit the number of your sex partner, use condoms, and if you think you are infected, avoid any sexual contact and visit a local STD clinic, hospital, or your doctor inmediately ...

1998 Sexually Transmitted Diseases Guidelines: Diseases Characterized By Genital Ulcers
Management of Patients Who Have Genital Ulcers ...

A Request for Redress of the Wrongs of Tuskegee
The Tuskegee Syphilis Study Legacy Commitee Report. In January 1996, the Tuskegee Syphilis Study Legacy Committee met at Tuskegee University to explore how the government and the nation could publicly address the Tuskegee Syphilis Study and its impact. The final report of the Committee from May 20, 1996 is abstracted and presented in its entirety below ...

Diagnosis and Management of Maternal and Congenital Syphilis
Wisconsin Association for Perinatal Care. Several factors have been cited as contributors to the increase in congenital syphilis ... There is an epidemic use of crack cocaine indirectly resulting in increased rates of sexually transmitted diseases, including syphilis ... The center for Disease Control (CDC) changed its definition for reporting of congenital syphilis in 1989 and this has led to more identified cases of congenital syphilis ...

The Great Sourge': Syphilis as a medical problem and moral metaphor, 1880-1916
Lesley A Hall. Wellcome Institute for the History of Medicine, London

Congenital Syphilis
Images

Center of Disease Control. Guidelines for the Prevention and Control of Congenital Syphilis
MMWR Supplements. January 15, 1988 / 37 (S-1); 1-13. Congenital syphilis causes fetal or perinatal death in 40% of the infants affected. The condition was well described in the 15th century ... Congenital syphilis surveillance should be conducted at the local, state, and national levels ... Two other aspects of surveillance for congenital syphilis warrant emphasis. first, a sensitive system is needed ... Second, state health departments should mantain a central registry of patients ...

[*][S] Public Health Fact Sheet: Syphilis
Massachusets Department of Public Health. What is syphilis? Who gets syphilis? What are the symptoms of syphilis? How soon the symptoms appear? ...

[S] What is syphilis?
Sexual Healing. A guide to men's sexual health
How do I know if I have syphilis? What can be done if I have syphilis? How can I avoid syphilis? ...

[*][P] Surveillance for Geographic and Secular Trends in Congenital Syphilis - 1983-1991
CDC, MMWR 42(SS-6);59-71, 12/17/1993
Ruth Ann Dunn, M.D. et al.
Results: During the period 1983-1991, 12,151 CS cases were reported. Before 1988, regional CS incidence increased 35%-131% annually. Larger increases occurred in the Northeast (578%) in 1989 and in the South (178%), Midwest (244%), and West (777%) in 1990. Within regions, these larger increases were temporally related to increases in P&S syphilis in women and changes to a more sensitive CS case definition ... The increase in the number of CS cases among infants less than 1 year of age probably represents a true increase in the incidence of CS in the United States ... Access to and use of prenatal care by women at high risk for syphilis may have decreased during the 1980s, thus reducing their chances of receiving adequate treatment during pregnancy ... Some of the increase in the number of CS cases since 1988 may be explained by changes in CS reporting practices ... The Birth Defects Monitoring Program (BDMP) is a CDC national surveillance system that samples hospital discharge data on U.S. births ... The sample is neither random nor completely geographically representative. The percentages of live births sampled in each region are approximately 13% in the Northeast, 22% in the Midwest, 8% in the South, and 19% in the West ...